Triazinone and diazinone derivatives useful as Hsp90 inhibitors
摘要
The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound.
申请公布号
AU2008232354(B2)
申请公布日期
2012.06.28
申请号
AU20080232354
申请日期
2008.03.24
申请人
SYNTA PHARMACEUTICALS CORP.
发明人
PRZEWLOKA, TERESA;SONG, MINGHU;QIN, SHUZHEN;FOLEY, KEVIN;YING, WEIWEN;LEE, CHI-WAN;DU, ZHENJIAN;ZHOU, DAN