MDCK-DERIVED CELL LINES ADAPTED TO SERUM-FREE CULTURE AND SUSPENSION CULTURE AND METHOD FOR PREPARING VACCINE VIRUS USING THE CELLS
摘要
Disclosed is a Madin-Darby canine kidney (MDCK)-derived cell line. The MDCK-derived cell line is derived from MDCK cells deposited under accession number ATCC CCL-34. The MDCK-derived cell line can be prepared by serum-free culture and suspension culture. Preferably, the MDCK-derived cell line has low or no tumorigenicity. The MDCK-derived cell line is preferably selected from MDCK Sky1023, MDCK Sky10234 and MDCK Sky3851. Further disclosed are a culture method for growing the MDCK-derived cells and a method for producing a vaccine virus using the MDCK-derived cells.
申请公布号
WO2012033328(A3)
申请公布日期
2012.06.28
申请号
WO2011KR06589
申请日期
2011.09.06
申请人
SK CHEMICALS CO., LTD.;PARK, YONG WOOK;LEE, KUN SE;LEE, BONG-YONG;PARK, MAHNHOON;KIM, HUN;KIM, YUN-HEE;LEE, SU-JEEN
发明人
PARK, YONG WOOK;LEE, KUN SE;LEE, BONG-YONG;PARK, MAHNHOON;KIM, HUN;KIM, YUN-HEE;LEE, SU-JEEN