USE OF A RNA INTERFERENCE COMPOUND IN THE PREPARATION OF MEDICAMENTS FOR TREATING A DISORDER OF THE CENTRAL NERVOUS SYSTEM, PHARMACEUTICAL COMPOSITIONS FOR INTRANASAL ADMINISTRATION COMPRISING ONE OR A PLURALITY OF SINA TARGETING A GENE EXPRESSED IN THE CNS. AND METHODS OF REDUCING EXPRESSION OF A TARGET GENE IN THE CNS OF A NON-HUMAN MAMMAL

摘要

Methods and compositions for the treatment of pathologic conditions of the central nervous system (CNS) by means of intranasal administration of a composition that modulates, by means of RNA interference, the expression and/or activity of genes involved in above-mentioned conditions.