发明名称 |
LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF |
摘要 |
The invention provides liposomes containing nonglycosidic ceramides within their bilayers, and compositions thereof. These liposomes activate murine iNKT cells and induce dendritic cell (DC) maturation, both in vitro and in vivo at an efficacy that is comparable to their corresponding soluble nonglycosidic ceramides. Also provided are methods for treating diseases using the liposomes and compositions of the invention. |
申请公布号 |
WO2012088414(A1) |
申请公布日期 |
2012.06.28 |
申请号 |
WO2011US66840 |
申请日期 |
2011.12.22 |
申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD.;CERUNDOLO, VINCENZO;EASTMAN, SIMON |
发明人 |
CERUNDOLO, VINCENZO;EASTMAN, SIMON |
分类号 |
A61K39/00;A61K39/39 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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