发明名称 |
METHODS AND SYSTEMS FOR PHYLOGENETIC ANALYSIS |
摘要 |
The present invention discloses methods and systems for designing and using organism-specific and/or operational taxon unit (OTU)-specific probes. The methods and systems allow for detecting, identifying and quantitating a plurality of biomolecules or microrganisms in a sample based on the hybridization or binding of target molecules in the sample with the probes. Some embodiments provide methods of selecting an oligonucleotide probe specific for a node on a clustering tree. Other embodiments provide methods of selecting organism-specific or OTU-specific oligonucleotide probes for use in accurately detecting a plurality of organisms in a sample with high confidence. Some embodiments provide methods and systems to detect the presence of a rare OTU in a sample. |
申请公布号 |
US2012165215(A1) |
申请公布日期 |
2012.06.28 |
申请号 |
US201013379839 |
申请日期 |
2010.06.25 |
申请人 |
ANDERSEN GARY L.;DESANTIS TODD Z.;BRODIE EOIN;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ANDERSEN GARY L.;DESANTIS TODD Z.;BRODIE EOIN |
分类号 |
C40B30/04;C40B40/06 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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