发明名称 |
A DRUG ELUTING PATCH FOR THE TREATMENT OF LOCALIZED TISSUE DISEASE OR DEFECT |
摘要 |
A polymeric matrix for delivery of an HMG CoA reductase inhibitor such as a statin to tissue such as cardiac tissue in need thereof for the treatment or prevention of a disease or defect such as atrial fibrillation has been developed. In the preferred embodiment, a statin is delivered by means of a patch sutured to cardiac tissue at the time of cardiothoracic surgery. In the most preferred embodiment, the patch is a biodegradable material providing controlled or sustained release over a prolonged period of time, such as a week. Suitable materials include extracellular matrix, or other biodegradable hydrogels or polymeric materials providing sustained or controlled release of statin at the site of application. |
申请公布号 |
WO2012087606(A1) |
申请公布日期 |
2012.06.28 |
申请号 |
WO2011US64115 |
申请日期 |
2011.12.09 |
申请人 |
SAINT JOSEPH'S TRANSLATIONAL RESEARCH INSTITUTE, INC.;SINGH, JAIPAL;CHRONOS, NICOLAS |
发明人 |
SINGH, JAIPAL;CHRONOS, NICOLAS |
分类号 |
A61K9/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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