发明名称 |
FACTOR H BINDING PEPTIDES AND USES THEREOF |
摘要 |
<p>Factor H-binding peptides that binds to a region of factor H that does not impede the complement-inhibitory activity of factor H are disclosed. When immobilized onto the surface of a biomaterial, these peptides recruit factor H, resulting in a substantial inhibition of biomaterial-induced complement activation in a biological substance exposed to the biomaterial.</p> |
申请公布号 |
WO2012087925(A1) |
申请公布日期 |
2012.06.28 |
申请号 |
WO2011US65822 |
申请日期 |
2011.12.19 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;LAMBRIS, JOHN D. |
发明人 |
LAMBRIS, JOHN D. |
分类号 |
C07K7/06;A61K38/04;A61L27/22;C07K7/08 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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