发明名称 BENZISOTHIAZOLE-1,1-DIOXIDE ACTING AS ANTAGONIST TO VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF
摘要 <P>PROBLEM TO BE SOLVED: To provide a compound particularly useful for the treatment of pain, inflammatory hyperalgesia, and urinary dysfunctions, such as bladder hypersensitivity and urinary incontinence. <P>SOLUTION: A compound having a formula (I) or a pharmaceutically acceptable salt thereof, a prodrug, or a salt of the prodrug is disclosed (in the formula: R<SP POS="POST">1</SP>, R<SP POS="POST">2</SP>and R<SP POS="POST">3</SP>are selected from a group consisting of hydrogen, halogen, alkyl and haloalkyl; L is a bond or a 1-6C alkyl; and each of A and G is a ring selected from a group consisting of cycloalkyl, cycloalkenyl, heterocycle, aryl and heteroaryl). <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012121887(A) 申请公布日期 2012.06.28
申请号 JP20120001109 申请日期 2012.01.06
申请人 ABBOTT LAB 发明人 BROWN BRIAN S;KEDDY RYAN G;LEE CHIH-HUNG
分类号 C07D417/04;A61K31/454;A61K31/46;A61K31/506;A61K31/55;A61P13/02;A61P13/10;A61P25/04;A61P29/00;A61P43/00;C07D417/14;C07D451/02 主分类号 C07D417/04
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