发明名称 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES
摘要 The present invention relates to 3,8-diaza-bicyclo[4.2.0]oct-3-yl amide derivatives of formula (I), wherein the relative configuration of the diazabicyclooctane moiety is cis; and wherein Ar1, and Ar2 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.
申请公布号 WO2012085857(A1) 申请公布日期 2012.06.28
申请号 WO2011IB55846 申请日期 2011.12.21
申请人 ACTELION PHARMACEUTICALS LTD;BOSS, CHRISTOPH;BROTSCHI, CHRISTINE;HEIDMANN, BIBIA;SIFFERLEN, THIERRY;WILLIAMS, JODI T. 发明人 BOSS, CHRISTOPH;BROTSCHI, CHRISTINE;HEIDMANN, BIBIA;SIFFERLEN, THIERRY;WILLIAMS, JODI T.
分类号 C07D471/04;A61K31/4353;A61P25/00 主分类号 C07D471/04
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