METHOD FOR PREDICTION OF ANTIVIRAL THERAPY (AVT) EFFICACY IN CHRONIC HEPATITIS B (CHB)

摘要

FIELD: medicine. ^ SUBSTANCE: for the purpose of prediction of a virusological reponse in the patients suffering chronic combined HBV/HCV-infection, the antiviral therapy of chronic hepatitis B is associated with measuring the blood serum TNF- cytokine content prior to and during the therapy on the 4-5th week and on the 7-8th week. If the initial TNF- cytokine content increased in 1.5 times and more on the 4-5th week of the therapy to be decreased in 1.5 times and more from the initial level on the 7-8th week of the therapy, a good efficacy of the prescribed therapy is predicted. If the initial increased in 1.5 times and less on the 4-5th week or the TNF- value decreased in 1.5 times and less from the initial level on the 7-8th week of the therapy, the therapy is predicted to be ineffective. ^ EFFECT: method allows early prediction of the antiviral therapy effect in the 4-8th weeks from the beginning of the therapy. ^ 2 dwg, 2 ex