发明名称 |
Multiple gene expression including sorf contructs and methods with polyproteins, pro-proteins, and proteolysis |
摘要 |
Disclosed is an expression vector for expressing a recombinant protein, comprising a coding sequence for a polyprotein, wherein the polyprotein comprises at least a first and a second protein segment, wherein said protein segments are separated by a protein cleavage site therebetween, wherein the protein cleavage site comprises a self processing peptide cleavage sequence, a signal peptide cleavage sequence, or a protease cleavage sequence; and wherein said coding sequence is expressible in a host cell and is cleaved within the host cell. |
申请公布号 |
EP2468768(A2) |
申请公布日期 |
2012.06.27 |
申请号 |
EP20120154514 |
申请日期 |
2006.07.21 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
CARSON, GERALD R.;GION, WENDY;SALFELD, JOCHEN G.;GU, JIJIE;REGIER, DEAN A.;KUNES, YUNE |
分类号 |
C12N15/63;C12P21/06;C07H21/02;C07H21/04;C07K16/00;C07K16/18;C12N1/18;C12N5/07;C12N5/071;C12N15/00;C12N15/10;C12P21/02;C12P21/08 |
主分类号 |
C12N15/63 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|