发明名称 |
Process for the preparation of lapatinib and the salts thereof |
摘要 |
<p>The present invention refers to a new process for the synthesis of the pharmaceutical active ingredient Lapatinib and the salts thereof. In particular, the present synthesis is performed using intermediates in which the hydroxyl function is protected by the tetrahydropyranyl group hence entailing greater solubility of the intermediates in the common organic solvents.</p> |
申请公布号 |
EP2468745(A1) |
申请公布日期 |
2012.06.27 |
申请号 |
EP20120158120 |
申请日期 |
2012.03.05 |
申请人 |
F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. |
发明人 |
FONTANA, FRANCESCO |
分类号 |
C07D405/04;A61K31/517;A61P35/00;C07D405/14 |
主分类号 |
C07D405/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|