发明名称 SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS
摘要 Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
申请公布号 EP2467380(A2) 申请公布日期 2012.06.27
申请号 EP20100810564 申请日期 2010.08.18
申请人 VENTIRX PHARMACEUTICALS, INC.;ARRAY BIOPHARMA, INC. 发明人 HOWBERT, JAMES, JEFFRY;DIETSCH, GREGORY;HERSHBERG, ROBERT;BURGESS, LAURENCE, E.;DOHERTY, GEORGE, A.;EARY, C. TODD;GRONEBERG, ROBERT, D.;JONES, ZACHARY
分类号 C07D403/10;A61K31/4025;A61K31/55;A61P31/00;A61P35/00;C07D223/14;C07D401/14;C07D403/14 主分类号 C07D403/10
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