发明名称 SYNTHESIS OF CHIRALLY PURE SUBSTITUTED BENZOTHIAZOLE DIAMINES
摘要 FIELD: chemistry. ^ SUBSTANCE: invention discloses methods of producing chirally pure substituted 4,5,6,7-tetrahydrobenzothiazole diamines such as, for example, (6R)-2-amino-4.5,6,7-tetrahydro-6-(propylamino)benzothiazole, and salts thereof, as well as purification of the predominant enantiomer of substituted 4,5,6,7-tetrahydrobenzothiazole diamines from enantiomer-rich mixtures of substituted 4,5,6,7-tetrahydrobenzothiazole diamines. ^ EFFECT: improved method of producing chirally pure substituted 4,5,6,7-tetrahydrobenzothiazole diamines. ^ 23 cl, 25 ex, 6 tbl, 7 dwg
申请公布号 RU2454409(C2) 申请公布日期 2012.06.27
申请号 RU20090137925 申请日期 2008.03.14
申请人 NOPP N'JUROSAJENSIZ, INK. 发明人 RADZHE PRASAD;GADIKOTA RADZHENDRAKUMAR REDDI;CHEHN' TSZJAN'-SE;LAPINA OL'GA;MAKKOLL DZHON M.
分类号 A61K31/428;C07D277/82 主分类号 A61K31/428
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