发明名称 METHOD FOR OBTAINING MICRO- AND NANO-DISPERSE SYSTEMS
摘要 The invention relates to a method for obtaining micro- and nanodisperse systems. In particular, it relates to a method that allows said systems, such as liposomes, emulsions and suspensions, to be obtained with a size of less than 50mm, and preferably less than 1mm, and with improved stability properties over time, which includes the stages of a) Dissolving or suspending a compound C in a fluid A, to obtain a mixture A, in the form of a solution or dispersion; b) Thermostatising said mixture A to a temperature of between -50~C and 200~C; c) Adding a fluid B to mixture A until a pressure P is obtained; and it is characterised in that in said stage (c) formation of the solution AB occurs and because it includes, d) Reducing the pressure of solution AB to a pressure lower than or equal to 100 bars, and then e) Adding a fluid E, in which fluid A is miscible and in which compound C is partially or totally insoluble at atmospheric pressure, with said fluid E acting as a crystallisation interruption agent.
申请公布号 CA2566960(C) 申请公布日期 2012.06.26
申请号 CA20062566960 申请日期 2006.01.03
申请人 发明人
分类号 B01J13/00;A61H9/00 主分类号 B01J13/00
代理机构 代理人
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