发明名称 Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds
摘要 This invention is directed to methods of preventing or treating neurological or neuropathic diseases or conditions associated with excessive inflammation, neurodegeneration, neuro-remodeling, and axonal/neurite retraction. Particularly, this invention relates to methods treating neurological or neuropathic diseases such as cerebral ischemia, stroke, neuropathic pain, spinal cord injury, Alzheimer's disease, and multiple sclerosis, using novel rho kinase inhibitor compounds. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel rho kinase inhibitor compound to treat the disease.
申请公布号 US8207195(B2) 申请公布日期 2012.06.26
申请号 US20090492848 申请日期 2009.06.26
申请人 NAVRATIL TOMAS;LAMPE JOHN W.;FULCHER EMILEE H.;PETERSON WARD M.;INSPIRE PHARMACEUTICALS, INC. 发明人 NAVRATIL TOMAS;LAMPE JOHN W.;FULCHER EMILEE H.;PETERSON WARD M.
分类号 A61K31/47;A61K31/40;A61K31/415 主分类号 A61K31/47
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