发明名称 |
Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells |
摘要 |
The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases. |
申请公布号 |
US8206701(B2) |
申请公布日期 |
2012.06.26 |
申请号 |
US20030665111 |
申请日期 |
2003.09.16 |
申请人 |
SCHENDEL DOLORES;WANK RUDOLF;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH) |
发明人 |
SCHENDEL DOLORES;WANK RUDOLF |
分类号 |
A61K48/00;C12N5/10;A61K35/12;A61K39/00;A61P35/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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