发明名称 |
Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors |
摘要 |
<p>This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.</p> |
申请公布号 |
AU2010333435(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
AU20100333435 |
申请日期 |
2010.12.15 |
申请人 |
H. LUNDBECK A/S |
发明人 |
PUSCHL, ASK;NIELSEN, JACOB;KEHLER, JAN;KILBURN, JOHN PAUL;MARIGO, MAURO;LANGGARD, MORTEN |
分类号 |
C07D471/04;A61K31/519;A61P25/00;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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