N-ALKYL OR N-ARYL SUBSTITUTED GUANIDE AND BIGUANIDE COMPOUNDS AND METHODS OF THEIR USE

摘要

The present invention provides N-aryl or N-alkyl guanide and biguanide containing compounds having the structure X. or the structure XI. These compounds may be synthesized by the addition of the respective guanide, biguanide or phenylguanide groups to polyamines containing primary and/or secondary amines. The present invention includes methods of using these compounds for the treatment and/or prevention of bacterial infection, HIV infection, and cancer and for the promotion of stem cell mobilization, wound healing, hematopoiesis, and skin rejuvenation.