发明名称 |
RECOMBINANT HOST CELLS COMPRISING PHOSPHOKETOLASES |
摘要 |
The present invention is related to recombinant host cells comprising: (i) at least one deletion, mutation, and/or substitution in an endogenous gene encoding a polypeptide that converts pyruvate to acetaldehyde, acetyl-phosphate or acetyl-CoA; and (ii) a heterologous polynucleotide encoding a polypeptide having phosphoketolase activity. The present invention is also related to recombinant host cells further comprising (iii) a heterologous polynucleotide encoding a polypeptide having phosphotransacetylase activity. |
申请公布号 |
US2012156735(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
US201113161168 |
申请日期 |
2011.06.15 |
申请人 |
DAUNER MICHAEL;MAGGIO-HALL LORI ANN;TOMB JEAN-FRANCOIS;BUTAMAX(TM) ADVANCED BIOFUELS LLC |
发明人 |
DAUNER MICHAEL;MAGGIO-HALL LORI ANN;TOMB JEAN-FRANCOIS |
分类号 |
C12P7/16;C12N1/19;C12N1/21;C12N15/63;C12P7/18;C12P7/26;C12P7/46;C12P7/56;C12P13/06;C12P13/08 |
主分类号 |
C12P7/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|