发明名称 GLP-2 FORMULATION
摘要 <P>PROBLEM TO BE SOLVED: To provide formulations of GLP-2 peptides and analogues thereof exhibiting superior stability during storage and/or exposure to high temperature. <P>SOLUTION: The GLP-2 peptide formulation contains a sufficient amount of phosphate buffer to adjust a pH of the formulation to a physiologically acceptable level, L-histidine, and an extender selected from a group consisting mannitol and sucrose. The pH of the formulation is preferably 6.0 or higher, and more preferably 6.9-7.9. Concentration of the GLP-2 peptide or the analogue thereof is preferably 0.1-50 mg/ml. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012116861(A) 申请公布日期 2012.06.21
申请号 JP20120027323 申请日期 2012.02.10
申请人 NPS PHARMACEUTICALS INC 发明人 ISAACS INDU J
分类号 A61K9/19;A61K38/00;A61K38/26;A61K45/00;A61K47/02;A61K47/04;A61K47/10;A61K47/18;A61K47/22;A61K47/26;A61P1/00;A61P1/04;A61P43/00 主分类号 A61K9/19
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