摘要 |
<P>PROBLEM TO BE SOLVED: To provide formulations of GLP-2 peptides and analogues thereof exhibiting superior stability during storage and/or exposure to high temperature. <P>SOLUTION: The GLP-2 peptide formulation contains a sufficient amount of phosphate buffer to adjust a pH of the formulation to a physiologically acceptable level, L-histidine, and an extender selected from a group consisting mannitol and sucrose. The pH of the formulation is preferably 6.0 or higher, and more preferably 6.9-7.9. Concentration of the GLP-2 peptide or the analogue thereof is preferably 0.1-50 mg/ml. <P>COPYRIGHT: (C)2012,JPO&INPIT |