PREGNANE GLYCOSIDE COMPOUNDS CONTAINING ORTHOESTER GROUPS AND USE THEREOF

摘要

The present invention relates to pregnane glycoside compounds containing orthoester groups, pharmaceutical compositions containing the compounds, and use thereof in the preparation of an immunosuppressant. More particularly, disclosed are pregnane glycoside compounds containing orthoester groups extracted from Periploca plants, pharmaceutical compositions containing the compounds, and use thereof in the preparation of an immunosuppressant for prevention and/or treatment of immunological rejection reactions following cell/organ transplantation or autoimmune diseases, wherein the autoimmune diseases comprise rheumatoid arthritis, multiple sclerosis and autoimmune hepatitis and the like.