METHODS OF MAKING CELL CARRIER

摘要

A method of making a carrier for growing cells, comprises providing a polymer film; embossing on one or more sides of the polymer film with an embossing roller comprising patterned surface; generating a pattern of structured indentation on one or more side of the polymer film; and discretizing the patterned polymer film into a plurality of portions. The embossing pattern generates relief features on the carrier surface. An alternative method of making a carrier for growing cells is also provided, wherein the method comprises, extruding a polymer film; embossing on one or more sides of the polymer film with a roller comprising patterned surface; generating a pattern of structured indentation on one or more side of the polymer film; imparting a surface treatment to the film comprising one or more of corona discharge treatment, gas plasma treatment, chemical functionalization or coating; and discretizing the treated polymer film into a plurality of portions.