发明名称 |
RNA APTAMER FOR TEIOCOIC ACID IN STAPHYLOCOCCUS AUREUS |
摘要 |
The present invention relates to a RNA aptamer for teiocoic acid in staphylococcus aureus, and more particularly, to a RNA aptamer that specifically binds the teiocoic acid in staphylococcus aureus, which is useful for detecting the teiocoic acid in staphylococcus aureus, a primary cause for food poisoning, etc., by having a base sequence of sequence number 1, in which the hydroxyl group of uracil (U) and cytosine (C) are substituted with a fluoro group, which can prevent rotting of food products by specifically binding to and suppressing the activity of the teiocoic acid in staphylococcus aureus, and which is useful for preventing and treating a disease selected from a group consisting of staphylococcal pneumonia, septicemia, osteomyelitis, staphylococcal enteritis, food poisoning, staphylococcal scalded skin syndrome (SSSS), and toxic shock syndrome (TSS). |
申请公布号 |
WO2012081908(A2) |
申请公布日期 |
2012.06.21 |
申请号 |
WO2011KR09631 |
申请日期 |
2011.12.14 |
申请人 |
KOREA FOOD RESEARCH INSTITUTE;CHO, YONG JIN;KIM, CHUL JIN;KIM, NAM SOO;KIM, CHONG TAI;MAENG, JIN SOO;LEE, SEONG WOOK;LEE, YOUNG JU;HAN, SEUNG RYUL |
发明人 |
CHO, YONG JIN;KIM, CHUL JIN;KIM, NAM SOO;KIM, CHONG TAI;MAENG, JIN SOO;LEE, SEONG WOOK;LEE, YOUNG JU;HAN, SEUNG RYUL |
分类号 |
C12N15/115;A61K31/7105;C12Q1/68;C12R1/44 |
主分类号 |
C12N15/115 |
代理机构 |
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