发明名称 |
NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF |
摘要 |
A nanoparticle composition is provided, wherein the composition comprises a nanoparticulate metal oxide; and a phosphorylated polyol comprising at least two phosphate groups. The polyol comprises one or more hydrophilic groups selected from the group consisting of polyethylene ether moieties, polypropylene ether moieties, polybutylene ether moieties, and combinations of two or more of the foregoing hydrophilic moieties. A method of making the nanoparticle composition is also provided. The nanoparticle compositions provided by the present invention may be used as contrast agents in medical imaging techniques such as X-ray and magnetic resonance imaging.
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申请公布号 |
CA2819795(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
CA20112819795 |
申请日期 |
2011.12.14 |
申请人 |
GENERAL ELECTRIC COMPANY |
发明人 |
BALES, BRIAN C.;HAY, BRUCE ALLAN;LUTTREL, MICHAEL TODD;KANDAPALLIL, BINIL ITTY IPE |
分类号 |
A61K49/18;B82Y5/00;B82Y15/00 |
主分类号 |
A61K49/18 |
代理机构 |
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