| 发明名称 |
2-AMINO-4-ARYLTHIAZOLE COMPOUNDS AS TRPAI ANTAGONISTS |
| 摘要 |
The present invention is related to 2-amino-4-arylthiazole derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.
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| 申请公布号 |
US2012157411(A1) |
申请公布日期 |
2012.06.21 |
| 申请号 |
US201113327128 |
申请日期 |
2011.12.15 |
| 申请人 |
KUMAR SUKEERTHI;THOMAS ABRAHAM;CHAUDHARI SACHIN SUNDARLAL;KANSAGRA BIPIN PARSOTTAM;YEMIREDDY VENKATA RAMANA;KHAIRATKAR-JOSHI NEELIMA;MUKHOPADHYAY INDRANIL;GUDI GIRISH;GLENMARK PHARMACEUTICALS, S.A. |
发明人 |
KUMAR SUKEERTHI;THOMAS ABRAHAM;CHAUDHARI SACHIN SUNDARLAL;KANSAGRA BIPIN PARSOTTAM;YEMIREDDY VENKATA RAMANA;KHAIRATKAR-JOSHI NEELIMA;MUKHOPADHYAY INDRANIL;GUDI GIRISH |
| 分类号 |
A61K31/519;A61K31/675;A61P1/00;A61P1/04;A61P1/08;A61P9/10;A61P11/00;A61P11/06;A61P11/14;A61P13/00;A61P17/02;A61P17/04;A61P17/06;A61P25/00;A61P25/04;A61P25/06;A61P25/28;A61P29/00;C07D491/044;C07D495/04;C07F9/6561 |
主分类号 |
A61K31/519 |
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