发明名称 |
COMPOSITIONS AND METHODS FOR TREATING CANCER AND NEURODEGENERATIVE DISEASES |
摘要 |
<p>The present invention relates to compositions and methods for regulating ROC-mediated death-associated protein kinase (DAPk) activity. The compositions and methods of the present invention are useful for treating or ameliorating cancer as well as pathologies associated with neuronal cell death, such as epilepsy and hypoxia/ischemia acute brain injury. The present invention further relates to screening methods for identifying agents that regulate ROC-mediated DAPk activation.</p> |
申请公布号 |
WO2012081017(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
WO2011IL00950 |
申请日期 |
2011.12.14 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;KIMCHI, ADI;CARLESSI, RODRIGO |
发明人 |
KIMCHI, ADI;CARLESSI, RODRIGO |
分类号 |
G01N33/50;A61P25/00;A61P35/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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