AMORPHOUS POWDER AND POLYMORPH OF CARBAPENEM DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF

摘要

The present invention relates to an amorphous powder, a solvate, and a polymorph of a carbapenem derivative (4R,55,6S)3-[(3S,5S)-5-[(furan-2-ylmethyl)amino-formyl]3-pyrrolidine]thio-6-[(R)-1-hydroxyethyl]4-methyl-7-oxo-1-oxabicyclo[3.2.0]hept-2-enyl-2-carboxylic acid, that is, the compound of Formula (1), a preparation method therefor, a pharmaceutical composition containing the amorphous powder and/or the polymorph, and a use thereof in treatment and/or prevention of infectious diseases and in preparation of drugs for treating and/or preventing infectious diseases. Formula (1)