| 发明名称 |
NEPRILYSIN INHIBITORS |
| 摘要 |
In one aspect, the invention relates to compounds having the formula: (I) where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds. |
| 申请公布号 |
CA2819153(A1) |
申请公布日期 |
2012.06.21 |
| 申请号 |
CA20112819153 |
申请日期 |
2011.12.14 |
| 申请人 |
THERAVANCE, INC. |
发明人 |
SMITH, CAMERON;FLEURY, MELISSA;GENDRON, ROLAND;HUDSON, RYAN;HUGHES, ADAM D. |
| 分类号 |
C07D231/14;C07D231/20;C07D231/22;C07D231/40;C07D237/24;C07D239/36;C07D239/54;C07D249/04;C07D249/10;C07D249/12;C07D249/18;C07D257/04;C07D261/18;C07D263/34;C07D263/38 |
主分类号 |
C07D231/14 |
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