摘要 |
The invention relates to a method of using an inducible transgene in a cell, where the inducible transgene expresses a gene product having activity on a cell death or cell survival pathway. The method includes exposing the cell to an agent that is capable of inducing the inducible transgene but also has direct activity on a cell death or cell survival pathway, said exposing being carried out in a manner effective to induce expression of the transgene while substantially minimizing said direct activity of the agent. Host cells and kits for carrying out the method are also disclosed. |