发明名称 |
NEW-TYPE CHITOSAN-BASED HYBRID MACROMOLECULE AND A METHOD FOR PRODUCING OR USING THE MACROMOLECULE |
摘要 |
The invention discloses the synthesis of a new-type chitosan-based hybrid macromolecule and a method for producing or using the macromolecule. This macromolecule comprises an amphiphatic chitosan and a silicon-based coupling agent that is anchored by a chemical bonding. The method for producing the hybrid macromolecule can be easily operated under ambient environment. The produced macromolecule can be self-assembled in an aqueous environment to form a nanocarrier, and has the ability to efficiently encapsulate drugs for a subsequent sustained release purpose. This self-assembled hybrid nanocarrier demonstrated features of excellent biocompatibility, drug loading ability and cellular uptake efficiency. |
申请公布号 |
US2012153520(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
US201113101676 |
申请日期 |
2011.05.05 |
申请人 |
LIU DEAN-MO;TUNG TSAN-HUA;CHENG HONGWEI |
发明人 |
LIU DEAN-MO;TUNG TSAN-HUA;CHENG HONGWEI |
分类号 |
B01J13/02;C08B37/08 |
主分类号 |
B01J13/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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