发明名称 PROCESS FOR PREPARING NANOPARTICLES OF TWO POLYAMINO ACIDS OF OPPOSITE CHARGE, ONE OF THE TWO OF WHICH IS IN CHARGE SURPLUS
摘要 <p>The present invention relates to a novel process for preparing nanoparticles having a diameter of less than or equal to 500 nm, which comprises bringing a solution (1) comprising nanoparticles of a first polyelectrolyte in the charged state, bearing hydrophobic side groups, into contact with (2) at least a second polyelectrolyte which has a polarity opposite to that of the first polyelectrolyte, characterized in that the ratio Z of the number of cationic groups to the number of anionic groups in the mixture of the two polyelectrolytes is between 0.1 and 0.75 or between 1.3 and 2, and the total concentration by weight C of polyelectrolytes is strictly less than 2 mg/g of the mixture.</p>
申请公布号 WO2012080986(A1) 申请公布日期 2012.06.21
申请号 WO2011IB55727 申请日期 2011.12.16
申请人 FLAMEL TECHNOLOGIES;DROGOZ, ALEXANDRE;CONSTANCIS, ALAIN 发明人 DROGOZ, ALEXANDRE;CONSTANCIS, ALAIN
分类号 A61K9/51;A61K9/00;A61K9/10;A61K31/00;A61K39/00;A61K47/48;B82Y5/00 主分类号 A61K9/51
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