发明名称 |
PROCESS FOR PREPARING NANOPARTICLES OF TWO POLYAMINO ACIDS OF OPPOSITE CHARGE, ONE OF THE TWO OF WHICH IS IN CHARGE SURPLUS |
摘要 |
<p>The present invention relates to a novel process for preparing nanoparticles having a diameter of less than or equal to 500 nm, which comprises bringing a solution (1) comprising nanoparticles of a first polyelectrolyte in the charged state, bearing hydrophobic side groups, into contact with (2) at least a second polyelectrolyte which has a polarity opposite to that of the first polyelectrolyte, characterized in that the ratio Z of the number of cationic groups to the number of anionic groups in the mixture of the two polyelectrolytes is between 0.1 and 0.75 or between 1.3 and 2, and the total concentration by weight C of polyelectrolytes is strictly less than 2 mg/g of the mixture.</p> |
申请公布号 |
WO2012080986(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
WO2011IB55727 |
申请日期 |
2011.12.16 |
申请人 |
FLAMEL TECHNOLOGIES;DROGOZ, ALEXANDRE;CONSTANCIS, ALAIN |
发明人 |
DROGOZ, ALEXANDRE;CONSTANCIS, ALAIN |
分类号 |
A61K9/51;A61K9/00;A61K9/10;A61K31/00;A61K39/00;A61K47/48;B82Y5/00 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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