发明名称 |
MODULATION OF RESPONSE REGULATORS BY IMIDAZOLE DERIVATIVES |
摘要 |
The present disclosure provides methods and compositions useful for screening agents for activity in modulating response regulator signaling activity, which is, in turn, useful for determining whether these agents modulate biofilm formation or lowers the minimum inhibitory concentration (MIC) of an antibiotic, useful in determining or selecting optimum agents and/or agent dosages in modulating a biofilm of interest or lowering the minimum inhibitory concentration (MIC) of an antibiotic, and useful as a research tool for studying response regulators. |
申请公布号 |
WO2012058531(A3) |
申请公布日期 |
2012.06.21 |
申请号 |
WO2011US58277 |
申请日期 |
2011.10.28 |
申请人 |
NORTH CAROLINA STATE UNIVERSITY;MELANDER, CHRISTIAN;CAVANAGH, JOHN;THOMPSON, RICHELE |
发明人 |
MELANDER, CHRISTIAN;CAVANAGH, JOHN;THOMPSON, RICHELE |
分类号 |
C40B30/06;A61K31/415 |
主分类号 |
C40B30/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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