发明名称 |
6-SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS |
摘要 |
The present invention relates to substituted imidazopyrazine compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined in the claims, to methods of and intermediates for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
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申请公布号 |
CA2821819(A1) |
申请公布日期 |
2012.06.21 |
申请号 |
CA20112821819 |
申请日期 |
2011.12.13 |
申请人 |
BAYER INTELLECTUAL PORPERTY GMBH |
发明人 |
KOPPITZ, MARCUS;KLAR, ULRICH;JAUTELAT, ROLF;KOSEMUND, DIRK;BOHLMANN, ROLF;BADER, BENJAMIN;LIENAU, PHILIP;SIEMEISTER, GERHARD |
分类号 |
C07D487/04;A61K31/4985;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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