发明名称 5-HYDROXYMETHYLOXAZOLIDIN-2-ONE DERIVATIVES
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to compounds of general formula , where R1 denotes OH, OPO3H2 or OCOR5; R2 denotes H, OH or OPO3H2; A denotes N or CR6; R3 denotes fluorine; R4 denotes H, C1-3alkyl or C3-6cycloalkyl; R5 denotes an alanine residue; R6 denotes H, C1-6alkoxy group or halogen; and n=0 or 1; and to pharmaceutically acceptable salts of compounds of formula I. The invention also relates to a pharmaceutical composition having antibacterial activity, and to use of compounds of formula I to obtain a medicinal agent for preventing or treating bacterial infections. ^ EFFECT: compounds of formula I, having antibacterial activity. ^ 14 cl, 3 dwg, 2 tbl, 14 ex
申请公布号 RU2453546(C2) 申请公布日期 2012.06.20
申请号 RU20090121812 申请日期 2007.11.09
申请人 AKTELION FARMAS'JUTIKLZ LTD 发明人 KHUBSHVERLEN KRISTIAN;PANSHO FILIPP;SPEKLEN ZHAN-LJUK
分类号 A61K31/4545;A61K31/4709;A61K31/661;A61P31/04;C07D413/14;C07D471/04 主分类号 A61K31/4545
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