发明名称 Peptide vaccines for cancers expressing tumor-associated antigens
摘要 <p>The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 174, 178, 186, 194, 196,202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK and/or URLC10, e.g. cancers containing as an active ingredient one or more of these peptides. The peptides of the present invention find further utility as vaccines.</p>
申请公布号 EP2465867(A2) 申请公布日期 2012.06.20
申请号 EP20120151722 申请日期 2008.02.21
申请人 ONCOTHERAPY SCIENCE, INC. 发明人 TSUNODA, TAKUYA;OHSAWA, RYUJI
分类号 C07K14/47;A61K39/00;A61P35/00;C07K14/745;C12N5/10;G01N33/15;G01N33/50 主分类号 C07K14/47
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