发明名称 PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND
摘要 The present invention provides an industrially advantageous, simple, and efficient process for producing a key intermediate of a benzo[b][1,4]diazepine-2,4-dione compound, which is a therapeutic medicine for arrhythmia. The present invention relates to a process for producing a compound represented by formula (1), wherein each of R 1 , R 2 , R 3 and R 4 , which may be the same or different, represents a hydrogen atom or a lower alkyl group, the process including deprotecting a protective group (R 5 ) of a compound represented by formula (2), wherein R 1 , R 2 , R 3 and R 4 are as defined above, and R 5 represents a protective group of a hydroxy group.
申请公布号 KR20120065360(A) 申请公布日期 2012.06.20
申请号 KR20127007170 申请日期 2010.08.20
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 TSUJIMORI HISAYUKI;TAIRA SHINICHI;YUKAWA HIROTAKA;ABE KAORU
分类号 C07D243/12;A61K31/551;A61P9/06 主分类号 C07D243/12
代理机构 代理人
主权项
地址