| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: method comprises the following steps: reaction of 3-methylselenopropion aldehyde of formula (I): with an alkali metal cyanide of formula M+CN-, preferably in the presence of an alkali metal bisulphite salt of formula M+HSO3Çè-, where M denotes an alkali metal atom, in a polar protic solvent, to obtain 2-hydroxy-4-methylselenobutyronitrile of formula (II): , hydrolysis of the compound of formula (II) in the medium of hot concentrated sulphuric acid, in a polar protic solvent, to obtain the desirable compound of formula (IV): , or hydrolysis of the compound of formula (II) in the medium of hot concentrated sulphuric acid, in a polar protic solvent, to obtain a compound of formula (III): , which can be hydrolysed in the medium of hot concentrated strong acid to obtain a compound of formula (IV). The compound of formula (IV) can be converted to one of its salts after adding a physiologically acceptable base. The invention also discloses a method of preparing a mixture of 2-hydroxy-4-methylselenobutyric acid and 2-hydroxy-4-methylthiobutyric acid and use thereof, 2-hydroxy-4-methylselenobutyronitrile and use thereof, and a dietary composition. ^ EFFECT: invention simplifies production of 2-hydroxy-4-methylselenobutyric acid. ^ 17 cl, 7 ex |
