发明名称 |
Methods of using hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide |
摘要 |
Disclosed are hydrates and polymorphs of 4- [[(7R)-8-cyclopentyl-7 -ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide: as well as, processes for preparing them and their use as pharmaceutical compositions with antiproliferative activity. |
申请公布号 |
US8202867(B2) |
申请公布日期 |
2012.06.19 |
申请号 |
US20090478178 |
申请日期 |
2009.06.04 |
申请人 |
LINZ GUENTER;SIEGER PETER;KRAEMER GERD F.;HOFFMANN MATTHIAS;BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
LINZ GUENTER;SIEGER PETER;KRAEMER GERD F.;HOFFMANN MATTHIAS |
分类号 |
A61K31/4985;A61P35/00 |
主分类号 |
A61K31/4985 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|