发明名称 INTERNALIZING ANTI-CD74 ANTIBODIES AND METHODS OF USE
摘要 <p>The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.</p>
申请公布号 CA2478012(C) 申请公布日期 2012.06.19
申请号 CA20032478012 申请日期 2003.03.03
申请人 IMMUNOMEDICS, INC. 发明人 HANSEN, HANS;LEUNG, SHUI-ON;QU, ZHENGXING;GOLDENBERG, DAVID M.
分类号 C12N15/13;A61K39/00;A61K39/395;A61K47/48;A61K49/16;A61K51/10;A61P35/00;A61P35/02;A61P37/00;C07K16/28;C07K16/46;C12P21/08;G01N33/574 主分类号 C12N15/13
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