发明名称 Human Dickkopf-related protein and nucleic acid molecules and uses therefor
摘要 Novel Dkk and Dkk-related polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Dkk and Dkk-related proteins, the invention further provides isolated fusion proteins, antigenic peptides and antibodies. The invention also provides Dkk and Dkk-related nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Dkk and Dkk-related gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
申请公布号 US8202966(B2) 申请公布日期 2012.06.19
申请号 US20090616901 申请日期 2009.11.12
申请人 MCCARTHY SEAN A.;MILLENNIUM PHARMACEUTICALS, INC. 发明人 MCCARTHY SEAN A.
分类号 C07K14/475;A61K38/00;C07K14/47;C07K19/00;G01N33/53 主分类号 C07K14/475
代理机构 代理人
主权项
地址