The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
申请公布号
WO2012077097(A1)
申请公布日期
2012.06.14
申请号
WO2011IL00911
申请日期
2011.11.30
申请人
OMRIX BIOPHARMACEUTICALS LTD.;MINTZ, RONI;ORR, NADAV;NUR, ISRAEL