<p>The invention relates to fragments of the amino acid sequence of the cytosolic domain of IRE1. These fragments are able to interfere with the enzymatic activities of IRE1, and thereby to modulate the activity of IRE1, i.e. to specify and control IRE1 downstream signalling.</p>
申请公布号
WO2012076625(A1)
申请公布日期
2012.06.14
申请号
WO2011EP72136
申请日期
2011.12.07
申请人
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);CHEVET, ERIC;BOUCHECAREILH, MARION