发明名称 |
SHORT-CHAIN CATIONIC POLYAMINO ACID AND USE THEREOF |
摘要 |
The present invention provides a cationic polyamino acid suitable for a carrier that can form a stable complex with a nucleic acid under a physiological condition and release the nucleic acid in cells suitably. The cationic polyamino acid can associate with a nucleic acid and includes a cationic amino acid residue having a cationic group in a side chain and a hydrophobic amino acid residue having a hydrophobic group in a side chain. The cationic polyamino acid includes 1 to 20 units of the cationic amino acid residue and is represented by the following formula (1). The meaning of each symbol in the formula is as shown in the description.
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申请公布号 |
US2012149649(A1) |
申请公布日期 |
2012.06.14 |
申请号 |
US201113258663 |
申请日期 |
2011.02.23 |
申请人 |
KATO YASUKI;ISHII ATSUSHI;SHIBATA NAOYA;HAYASHI TATSUYUKI;KATAOKA KAZUNORI;MIYATA KANJIRO;NISHIYAMA NOBUHIRO;THE UNIVERSITY OF TOKYO;NANOCARRIER CO., LTD. |
发明人 |
KATO YASUKI;ISHII ATSUSHI;SHIBATA NAOYA;HAYASHI TATSUYUKI;KATAOKA KAZUNORI;MIYATA KANJIRO;NISHIYAMA NOBUHIRO |
分类号 |
A61K38/16;A61K38/08;A61K38/10;A61P43/00;C07K7/06;C07K7/08;C07K14/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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