发明名称 SHORT-CHAIN CATIONIC POLYAMINO ACID AND USE THEREOF
摘要 The present invention provides a cationic polyamino acid suitable for a carrier that can form a stable complex with a nucleic acid under a physiological condition and release the nucleic acid in cells suitably. The cationic polyamino acid can associate with a nucleic acid and includes a cationic amino acid residue having a cationic group in a side chain and a hydrophobic amino acid residue having a hydrophobic group in a side chain. The cationic polyamino acid includes 1 to 20 units of the cationic amino acid residue and is represented by the following formula (1). The meaning of each symbol in the formula is as shown in the description.
申请公布号 US2012149649(A1) 申请公布日期 2012.06.14
申请号 US201113258663 申请日期 2011.02.23
申请人 KATO YASUKI;ISHII ATSUSHI;SHIBATA NAOYA;HAYASHI TATSUYUKI;KATAOKA KAZUNORI;MIYATA KANJIRO;NISHIYAMA NOBUHIRO;THE UNIVERSITY OF TOKYO;NANOCARRIER CO., LTD. 发明人 KATO YASUKI;ISHII ATSUSHI;SHIBATA NAOYA;HAYASHI TATSUYUKI;KATAOKA KAZUNORI;MIYATA KANJIRO;NISHIYAMA NOBUHIRO
分类号 A61K38/16;A61K38/08;A61K38/10;A61P43/00;C07K7/06;C07K7/08;C07K14/00 主分类号 A61K38/16
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