发明名称 MEDICINAL COMPOSITION FOR IMPROVING ORAL ABSORPTION
摘要 <P>PROBLEM TO BE SOLVED: To provide inhibitors for degradation of a physiologically active peptide with a digestive enzyme. <P>SOLUTION: The invention relates to: the inhibitors for degradation of a physiologically active peptide comprises an aminoalkyl methacrylate copolymer E as an active ingredient; viscosity-lowering agents for a digestive tract mucosa and/or mucus layers distributed thereon which comprise the aminoalkyl methacrylate copolymer E as an active ingredient; and medicinal compositions for improving oral absorption which contain the physiologically active peptide and the aminoalkyl methacrylate copolymer E. The medicinal compositions make it possible to achieve an excellent oral absorbability of the physiologically active peptide conventionally considered to be hardly absorbed orally. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012111773(A) 申请公布日期 2012.06.14
申请号 JP20120019638 申请日期 2012.02.01
申请人 ASTELLAS PHARMA INC 发明人 WATANABE TOSHINORI;NAKANISHI TAKAYO;TAKEMURA YOSHIO;TSUTSUI YUUKI
分类号 A61K47/32;A61K9/00;A61K9/08;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K31/785;A61K38/11;A61K38/22;A61K38/23;A61K38/28;A61P43/00 主分类号 A61K47/32
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