发明名称 SUBSTITUTED ARYLAMINE COMPOUND AND THEIR USE AS 5-HT6 MODULATOR
摘要 <P>PROBLEM TO BE SOLVED: To provide 5-HT<SB POS="POST">6</SB>receptor antagonists. <P>SOLUTION: This invention relates to: novel arylamine compounds having the formula I and pharmaceutically acceptable salts and/or esters thereof; and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity-related disorders, e.g., cardiovascular disease, digestive disease, respiratory disease, cancer and type-II diabetes, and in treating psychological disorders such as schizophrenia. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012111784(A) 申请公布日期 2012.06.14
申请号 JP20120060984 申请日期 2012.03.16
申请人 EPIX DELAWARE INC 发明人 BECKER OREN;LOBERA MERCEDES;MELENDEZ ROSA E;SHARADENDU ANURAG;WU LAURENCE;YU XIANG Y;DHANOA DALE S;CHERUKU SRINIVASA RAO;MARANTZ YAEL;NOIMAN SILVIA;FICHMAN MERAV;SENDEROWITZ HANOCH;SHACHAM SHARON;SAHA ASHIS;ORBACH PINI
分类号 C07D295/12;A61K31/495;A61P1/00;A61P3/04;A61P3/10;A61P9/00;A61P11/00;A61P25/18;A61P35/00;A61P43/00 主分类号 C07D295/12
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