摘要 |
<P>PROBLEM TO BE SOLVED: To provide 5-HT<SB POS="POST">6</SB>receptor antagonists. <P>SOLUTION: This invention relates to: novel arylamine compounds having the formula I and pharmaceutically acceptable salts and/or esters thereof; and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity-related disorders, e.g., cardiovascular disease, digestive disease, respiratory disease, cancer and type-II diabetes, and in treating psychological disorders such as schizophrenia. <P>COPYRIGHT: (C)2012,JPO&INPIT |