RELEASE OF ENDOGENOUS IL7 BY THE INFUSION OF GENETICALLY MODIFIED CELLS FOR IMMUNE RECONSTITUTION

摘要

The present invention is related to new therapeutic approaches to improve the release of endogenous IL7 in order to obtain immune reconstitution in allogeneic transplantation settings, as well as in pathological conditions characterized by immune dysregulation, or in other immunotherapeutic settings including those in which a gene transfer procedure is required, such as the adoptive transfer of genetically engineered T-cells.