发明名称 |
Methods Of Reducing Eosinophil Levels |
摘要 |
The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung. |
申请公布号 |
US2012148575(A1) |
申请公布日期 |
2012.06.14 |
申请号 |
US201113177221 |
申请日期 |
2011.07.06 |
申请人 |
BIOWA, INC.;MEDLMMUNE, LLC |
发明人 |
KOIKE MASAMICHI;SPITALNY GEORGE L.;WHEELER ALISTAIR;WHITE BARBARA |
分类号 |
A61K39/395;A61P11/00;A61P11/06;C07K7/08;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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