发明名称 |
2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION |
摘要 |
This invention relates to compounds of formula (I), their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the 10 treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R3, R4, R6, R2,R7, R8, R9, Ra, Rb have meanings given in the description. |
申请公布号 |
WO2012076672(A1) |
申请公布日期 |
2012.06.14 |
申请号 |
WO2011EP72256 |
申请日期 |
2011.12.09 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;PRIEPKE, HENNING;KUELZER, RAIMUND;MACK, JUERGEN;PFAU, ROLAND;STENKAMP, DIRK;PELCMAN, BENJAMIN;ROENN, ROBERT;LUBRIKS, DIMITRIJS;SUNA, EDGARS |
发明人 |
PRIEPKE, HENNING;KUELZER, RAIMUND;MACK, JUERGEN;PFAU, ROLAND;STENKAMP, DIRK;PELCMAN, BENJAMIN;ROENN, ROBERT;LUBRIKS, DIMITRIJS;SUNA, EDGARS |
分类号 |
C07D235/30;A61K31/4184;A61P29/00;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/12;C07D409/14;C07D413/12;C07D417/12 |
主分类号 |
C07D235/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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