DEUTERATED 5-TRIDEUTEROMETHYL-6-METHYL-2-THIOXO-2,3-DIHYDROPYRIDIN -4(1H)-ONE COMPOUNDS AND METHOD FOR THE PREPARATION THEREOF

摘要

The invention defines deuterated compounds of formula (I), in which: R1 and R2 independently represent a hydrogen atom or a C1-C4 alkyl group substituted with an -OR4 group, R4 being a hydrogen atom or a phenyl-substituted C1-C3 alkyl group; an -NR5R6 group, R5 and R6 independently being a hydrogen atom, or a C1-C3 alkyl, tosyl or mesyl group; a -SR7 group, R7 being a hydrogen atom or a C1-C3 alkyl group; a -OCOR8 group, R8 being a C1-C3 alkyl or phenyl group; or a halogen atom; and D represents deuterium. The invention also defines a method for preparing said deuterated compounds, a pharmaceutical composition comprising said compounds and the use of said compounds in the pharmaceutical and analytical fields.